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Clinical application of whole transcriptome sequencing for the classification of patients with acute lymphoblastic leukemia. Walter W, et al. BMC Cancer. 2021 Aug 2;21(1):886.
The diverse landscape of fusion transcripts in 25 different hematological entities. Haferlach C et al. Leuk Lymphoma. 2021 Dec;62(13):3292-3295.
Comment on: Genome Sequencing as an Alternative to Cytogenetic Analysis in Myeloid Cancers (Duncavage et al. N Engl J Med 2021;384:924-935). Haferlach T et al. N Engl J Med. 2021 Jun 24;384(25):e106.
Analytical Demands to Use Whole-Genome Sequencing in Precision Oncology. Meggendorfer M et al. Semin Cancer Biol. 2021 Jun 10;S1044-579X(21)00179-6. Online ahead of print.
Clinical utility of whole-genome sequencing in precision oncology. Rosenquist R et al. Semin Cancer Biol. 2021 Jun 24;S1044-579X(21)00189-9. Online ahead of print.
Classification and Personalized Prognostic Assessment on the Basis of Clinical and Genomic Features in Myelodysplastic Syndromes. Bersanelli M et al. J Clin Oncol. 2021 Apr 10;39(11):1223-1233.
Whole transcriptome sequencing detects a large number of novel fusion transcripts in patients with AML and MDS. Stengel et al. Blood Adv. 2020 Nov 10;4(21):5393-5401.
Next-generation diagnostics for precision oncology: Preanalytical considerations, technical challenges, and available technologies. Walter et al. Semin Cancer Biol. 2020 Nov 7;S1044-579X(20)30220-0. Online ahead of print.
Molecular landscape and clonal architecture of adult myelodysplastic/myeloproliferative neoplasms. Palomo L et al. Blood. 2020 Oct 15;136(16):1851-1862.
WGS and WTS in leukaemia: A tool for diagnostics? Meggendorfer M et al. Best Pract Res Clin Haematol. 2020 Sep;33(3):101190.
Complex landscape of alternative splicing in myeloid neoplasms. Hershberger CE et al. Leukemia. 2021 Apr;35(4):1108-1120.
The combination of WGS and RNA-Seq is superior to conventional diagnostic tests in multiple myeloma: Ready for prime time? Höllein A et al. Cancer Genet. 2020 Apr;242:15-24.
Clonal haematopoiesis in patients with degenerative aortic valve stenosis undergoing transcatheter aortic valve implantation. Mas-Peiro S et al. Eur Heart J. 2020 Feb 21;41(8):933-939.
Genomic subtyping and therapeutic targeting of acute erythroleukemia. Iacobucci I et al. Nat Genet. 2019 Apr;51(4):694-704.
After another scientifically successful year, the MLL would like to summarize the findings of 2021. Walter W
Large-scale sequencing experience from the MLL 5K project. Walter W
Genomic & Transcriptomic Data Visualization. Walter W
Analysis of pharmacogenomic variants by WGS data for AML patients with altered response to treatment. Walter W
AML and MDS – the ever-expanding potential of genetics to define clinically relevant subclasses. Walter W
Leukaemia diagnosis: Realising the potential of whole transcriptome sequencing. Research Features. Health & Medicine. Walter W. 10 March 2022.
A Novel Machine Learning Based in silico Pathogenicity Predictor for Missense Variants in a Hematological Setting. Hutter et al. Blood (2019) 134 (Supplement_1): 2090.
News Release - 21 March 2022
News - July 2021